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MARINE_LEO_ Mom
@MarineLEOMom
12 February, 05:20
In response mars 1776 to his Publication
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The Mac
@TheMac
13 February, 05:47
In response MARINE_LEO_ Mom to her Publication
Le-Qing Wu and David Dickman from the Baylor College of Medicine have found neurons in a pigeon's brain that encode the properties of a magnetic field. They buzz in different ways depending on how strong the field is, and which direction it's pointing in.
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The Mac
@TheMac
13 February, 07:09
In response The Mac to his Publication
We show that the artificial field through an attached magnet will quickly disrupt the birds' ability to distinguish pole-ward from equator-ward headings, but that much stronger fields are necessary to disrupt their ability to detect the magnetic axis.
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The Mac
@TheMac
13 February, 07:10
In response The Mac to his Publication
We may finally know the secret to how migrating birds can sense Earth's magnetic fields: a molecule in their eyes called cryptochrome 4 that is sensitive to magnetism, potentially giving the animals an internal compass.
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The Mac
@TheMac
13 February, 07:14
In response The Mac to his Publication
Magnetoreception (also magnetoception) is a sense which allows an organism to detect a magnetic field to perceive direction, altitude or location. This sensory modality is used by a range of animals for orientation and navigation,[1] and as a method for animals to develop regional maps. In navigation, like in bird migration, magnetoreception deals with the detection of the Earth's magnetic field.
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The Mac
@TheMac
13 February, 07:14
In response The Mac to his Publication
Magnetoreception is present in bacteria, arthropods, molluscs, and members of all major taxonomic groups of vertebrates.[1] Humans are not thought to have a magnetic sense, but there is a protein (a cryptochrome) in the eye which could serve this function.[2]
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Edmun Whaley
@Rooffox
13 February, 07:16
In response The Mac to his Publication
thank you for being there
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The Mac
@TheMac
13 February, 07:18
In response Edmun Whaley to his Publication
Wild-Type Mac
Leptoshpaeria schematic
Leptosphaeria rhodopsin (Mac) is a blue-green light-activated proton pump derived from the fungus Leptosphaeria maculans. Mac and its variants allow for inhibition of neurons using blue-green light.
Mac Variants. Mac variants have been engineered to include enhancements such as:
Improved photocurrent amplitude
Example: eMac3.0
😉👍🏻
Leptoshpaeria schematic
Leptosphaeria rhodopsin (Mac) is a blue-green light-activated proton pump derived from the fungus Leptosphaeria maculans. Mac and its variants allow for inhibition of neurons using blue-green light.
Mac Variants. Mac variants have been engineered to include enhancements such as:
Improved photocurrent amplitude
Example: eMac3.0
😉👍🏻
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Edmun Whaley
@Rooffox
13 February, 07:24
In response The Mac to his Publication
excellent name
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The Mac
@TheMac
13 February, 08:46
In response Edmun Whaley to his Publication
Gene Therapy and Light-Sensing Protein Restores Vision in Mice
Using gene therapy, a newly developed light-sensing protein called the MCO1 opsin restores vision in blind mice when attached to retina bipolar cells.
https://www.genengnews.com/news/gene-therapy-and-light-sensing-protein-restores-vision-in-mice/Notice: Undefined index: tg1tga_access in /home/admin/www/anonup.com/themes/default/apps/timeline/post.phtml on line 396
The Mac
@TheMac
13 February, 08:47
In response The Mac to his Publication
Here, we report AAV2 assisted delivery of highly photosensitive multi-characteristic opsin (MCO1) into ON-bipolar cells of mice with retinal degeneration to allow activation by ambient light,” write the investigators.
“Rigorous characterization of delivery efficacy by different doses of AAV2 carrying MCO1 (vMCO1) into targeted cells showed durable expression over 6 months after delivery as measured by reporter expression.
“Rigorous characterization of delivery efficacy by different doses of AAV2 carrying MCO1 (vMCO1) into targeted cells showed durable expression over 6 months after delivery as measured by reporter expression.
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The Mac
@TheMac
13 February, 08:48
In response The Mac to his Publication
COVID-19 Vaccine, AAVCOVID | Mass. Eye and Ear
Development of gene-based COVID-19 vaccine, AAVCOVID, underway at Massachusetts Eye and Ear and Massachusetts General Hospital.
https://masseyeandear.org/covid-19/vaccineNotice: Undefined index: tg1tga_access in /home/admin/www/anonup.com/themes/default/apps/timeline/post.phtml on line 396
The Mac
@TheMac
13 February, 08:49
In response The Mac to his Publication
AAV1 is the optimal viral vector for optogenetic experiments in pigeons (Columba livia) | Communications Biology
Although optogenetics has revolutionized rodent neuroscience, it is still rarely used in other model organisms as the efficiencies of viral gene transfer differ between species and comprehensive viral transduction studies are rare. However, for comparative research, birds offer valuable model organi..
https://www.nature.com/articles/s42003-020-01595-9Notice: Undefined index: tg1tga_access in /home/admin/www/anonup.com/themes/default/apps/timeline/post.phtml on line 396
The Mac
@TheMac
13 February, 08:50
In response The Mac to his Publication
Two papers published today in Science find birds actually have a brain that is much more similar to our complex primate organ than previously thought. ... The new findings show that birds' do, in fact, have a brain structure that is comparable to the neocortex despite taking a different shape.
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The Mac
@TheMac
13 February, 08:51
In response The Mac to his Publication
Infectious-disease expert Margaret Chan, who hails from Hong Kong, has been nominated as the next director-general of the World Health Organization (WHO), based in Geneva, Switzerland. Chan, who has spent the last 18 months as assistant director-general for communicable diseases at WHO, is best known for her role in containing two fast-spreading viral outbreaks of bird flu and SARS in Hong Kong, where she was director of public health from 1994 to 2003. Her nomination, by the 34-member Executive Board, still needs to be ratified by the World Health Assembly tomorrow.
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The Mac
@TheMac
13 February, 08:52
In response The Mac to his Publication
As Blind as a Bat? Opsin Phylogenetics Illuminates the Evolution of Color Vision in Bats | Molecular Biology and Evolution | Oxford Academic
Abstract. Through their unique use of sophisticated laryngeal echolocation bats are considered sensory specialists amongst mammals and represent an excellent mo
https://academic.oup.com/mbe/article/36/1/54/5200383Notice: Undefined index: tg1tga_access in /home/admin/www/anonup.com/themes/default/apps/timeline/post.phtml on line 396
The Mac
@TheMac
13 February, 08:53
In response The Mac to his Publication
Echolocation. Animals such as bats and dolphins send out ultrasound waves and use their echoes, or reflected waves, to identify the locations of objects they cannot see. This is called echolocation. Animals use echolocation to find prey and avoid running into objects in the dark
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The Mac
@TheMac
13 February, 08:55
In response The Mac to his Publication
Quantum effect
The quantum dot mechanism of action is strikingly simple. While in the retina, the nanoparticles are stimulated by visible light entering the eye – and if a quantum dot is stimulated while it is in close proximity to a neural cell, it triggers an action potential in that cell which is interpreted as vision by the brain. Thus, the effect of photovoltaically active nanoparticles diffused throughout the retina is to electrically stimulate a large range and number of neuro-retinal cells.
The quantum dot mechanism of action is strikingly simple. While in the retina, the nanoparticles are stimulated by visible light entering the eye – and if a quantum dot is stimulated while it is in close proximity to a neural cell, it triggers an action potential in that cell which is interpreted as vision by the brain. Thus, the effect of photovoltaically active nanoparticles diffused throughout the retina is to electrically stimulate a large range and number of neuro-retinal cells.
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The Mac
@TheMac
13 February, 08:56
In response The Mac to his Publication
polarity (n.)
1640s, "the having two opposite poles," originally of magnets, from polar + -ity. The sense of "variation in certain physical properties so that in one direction they are the opposite of what they are in the opposite direction" is from 1670s.
1640s, "the having two opposite poles," originally of magnets, from polar + -ity. The sense of "variation in certain physical properties so that in one direction they are the opposite of what they are in the opposite direction" is from 1670s.
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The Mac
@TheMac
13 February, 08:56
In response The Mac to his Publication
Ion channels are pore-forming membrane proteins that allow ions to pass through the channel pore. Their functions include establishing a resting membrane potential,[1] shaping action potentials and other electrical signals by gating the flow of ions across the cell membrane, controlling the flow of ions across secretory and epithelial cells, and regulating cell volume. Ion channels are present in the membranes of all cells.[2][3] Ion channels are one of the two classes of ionophoric proteins, the other being ion transporters.[4]
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The Mac
@TheMac
13 February, 08:57
In response The Mac to his Publication
ionic bond
An ionic bond is formed by the complete transfer of some electrons from one atom to another. The atom losing one or more electrons becomes a cation—a positively charged ion. The atom gaining one or more electron becomes an anion—a negatively charged ion.
An ionic bond is formed by the complete transfer of some electrons from one atom to another. The atom losing one or more electrons becomes a cation—a positively charged ion. The atom gaining one or more electron becomes an anion—a negatively charged ion.
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The Mac
@TheMac
13 February, 08:58
In response The Mac to his Publication
late Middle English: from Latin pollutio(n- ), from the verb polluere (see pollute).
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The Mac
@TheMac
13 February, 09:01
In response The Mac to his Publication
In chemistry, polarity is a separation of electric charge leading to a molecule or its chemical groups having an electric dipole moment, with a negatively charged end and a positively charged end. Polar molecules must contain one or more polar bonds due to a difference in electronegativity between the bonded atoms.
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The Mac
@TheMac
13 February, 09:02
In response The Mac to his Publication
Nuclear magnetic resonance (NMR) is a physical phenomenon in which nuclei in a strong constant magnetic field are perturbed by a weak oscillating magnetic field (in the near field[1]) and respond by producing an electromagnetic signal with a frequency characteristic of the magnetic field at the nucleus. This process occurs near resonance, when the oscillation frequency matches the intrinsic frequency of the nuclei, which depends on the strength of the static magnetic field, the chemical environment, and the magnetic properties of the isotope involved; in practical applications with static magnetic fields up to ca. 20 tesla, the frequency is similar to VHF and UHF television broadcasts (60–1000 MHz).
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The Mac
@TheMac
13 February, 09:02
In response The Mac to his Publication
NMR results from specific magnetic properties of certain atomic nuclei. Nuclear magnetic resonance spectroscopy is widely used to determine the structure of organic molecules in solution and study molecular physics and crystals as well as non-crystalline materials. NMR is also routinely used in advanced medical imaging techniques, such as in magnetic resonance imaging (MRI).
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The Mac
@TheMac
13 February, 09:04
In response The Mac to his Publication
The most commonly used nuclei are 1
H
and 13
C
, although isotopes of many other elements can be studied by high-field NMR spectroscopy as well. In order to interact with the magnetic field in the spectrometer, the nucleus must have an intrinsic nuclear magnetic moment and angular momentum. This occurs when an isotope has a nonzero nuclear spin, meaning an odd number of protons and/or neutrons (see Isotope). Nuclides with even numbers of both have a total spin of zero and are therefore NMR-inactive.
H
and 13
C
, although isotopes of many other elements can be studied by high-field NMR spectroscopy as well. In order to interact with the magnetic field in the spectrometer, the nucleus must have an intrinsic nuclear magnetic moment and angular momentum. This occurs when an isotope has a nonzero nuclear spin, meaning an odd number of protons and/or neutrons (see Isotope). Nuclides with even numbers of both have a total spin of zero and are therefore NMR-inactive.
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The Mac
@TheMac
13 February, 09:05
In response The Mac to his Publication
A key feature of NMR is that the resonance frequency of a particular sample substance is usually directly proportional to the strength of the applied magnetic field. It is this feature that is exploited in imaging techniques; if a sample is placed in a non-uniform magnetic field then the resonance frequencies of the sample's nuclei depend on where in the field they are located. Since the resolution of the imaging technique depends on the magnitude of the magnetic field gradient, many efforts are made to develop increased gradient field strength.
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The Mac
@TheMac
13 February, 09:09
In response The Mac to his Publication
The principle of NMR usually involves three sequential steps:
The alignment (polarization) of the magnetic nuclear spins in an applied, constant magnetic field B0.
The perturbation of this alignment of the nuclear spins by a weak oscillating magnetic field, usually referred to as a radio-frequency (RF) pulse. The oscillation frequency required for significant perturbation is dependent upon the static magnetic field (B0) and the nuclei of observation.
The alignment (polarization) of the magnetic nuclear spins in an applied, constant magnetic field B0.
The perturbation of this alignment of the nuclear spins by a weak oscillating magnetic field, usually referred to as a radio-frequency (RF) pulse. The oscillation frequency required for significant perturbation is dependent upon the static magnetic field (B0) and the nuclei of observation.
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The Mac
@TheMac
13 February, 09:10
In response The Mac to his Publication
The detection of the NMR signal during or after the RF pulse, due to the voltage induced in a detection coil by precession of the nuclear spins around B0. After an RF pulse, precession usually occurs with the nuclei's intrinsic Larmor frequency and, in itself, does not involve transitions between spin states or energy levels.
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The Mac
@TheMac
13 February, 09:11
In response The Mac to his Publication
The two magnetic fields are usually chosen to be perpendicular to each other as this maximizes the NMR signal strength. The frequencies of the time-signal response by the total magnetization (M) of the nuclear spins are analyzed in NMR spectroscopy and magnetic resonance imaging. Both use applied magnetic fields (B0) of great strength, often produced by large currents in superconducting coils, in order to achieve dispersion of response frequencies and of very high homogeneity and stability in order to deliver spectral resolution, the details of which are described by chemical shifts, the Zeeman effect, and Knight shifts (in metals). The information provided by NMR can also be increased using hyperpolarization, and/or using two-dimensional, three-dimensional and higher-dimensional techniques.
NMR phenomena are also utilized in low-field NMR, NMR spectroscopy and MRI in the Earth's magnetic field (referred to as Earth's field NMR), and in several types of magnetometers.
NMR phenomena are also utilized in low-field NMR, NMR spectroscopy and MRI in the Earth's magnetic field (referred to as Earth's field NMR), and in several types of magnetometers.
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The Mac
@TheMac
13 February, 09:13
In response The Mac to his Publication
Earth's magnetic field, also known as the geomagnetic field, is the magnetic field that extends from Earth's interior out into space, where it interacts with the solar wind, a stream of charged particles emanating from the Sun. The magnetic field is generated by electric currents due to the motion of convection currents of a mixture of molten iron and nickel in Earth's outer core: these convection currents are caused by heat escaping from the core, a natural process called a geodynamo. The magnitude of Earth's magnetic field at its surface ranges from 25 to 65 μT (0.25 to 0.65 gauss).[3] As an approximation, it is represented by a field of a magnetic dipole currently tilted at an angle of about 11 degrees with respect to Earth's rotational axis, as if there were an enormous bar magnet placed at that angle through the center of Earth.
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The Mac
@TheMac
13 February, 09:21
In response The Mac to his Publication
The magnetic field
is generated by electric currents
due
to
the motion
of
convection
currents of
a mixture of
molten iron and nickel in Earth's outer core:
these convection currents are caused by heat
escaping from the
core"
is generated by electric currents
due
to
the motion
of
convection
currents of
a mixture of
molten iron and nickel in Earth's outer core:
these convection currents are caused by heat
escaping from the
core"
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The Mac
@TheMac
13 February, 09:22
In response The Mac to his Publication
Heat can be created from magnets by putting magnetic material into a high-frequency oscillating magnetic field that makes the magnet's polarity switch back and forth at a high-enough rate to produce noticeable friction.
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The Mac
@TheMac
13 February, 09:24
In response The Mac to his Publication
The Earth's magnetic field is generated in the fluid outer core
by a self-exciting dynamo process.
Electrical currents flowing in the slowly moving molten iron
generate the magnetic field.
?
by a self-exciting dynamo process.
Electrical currents flowing in the slowly moving molten iron
generate the magnetic field.
?
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Loret Alen
@Lorettamusic
13 February, 09:26
In response The Mac to his Publication
maybe its really mercury in there.
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The Mac
@TheMac
13 February, 03:10
In response Loret Alen to his Publication
White light, a combination of lights of different wavelengths
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The Mac
@TheMac
13 February, 03:11
In response The Mac to his Publication
Mercury (/ˈmɜːrkjʊri/; Latin: Mercurius [mɛrˈkʊrijʊs] (audio speaker iconlisten)) is a major god in Roman religion and mythology, being one of the 12 Dii Consentes within the ancient Roman pantheon. He is the god of financial gain, commerce, eloquence, messages, communication (including divination), travelers, boundaries, luck, trickery, and thieves; he also serves as the guide of souls to the underworld.
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The Mac
@TheMac
13 February, 03:13
In response The Mac to his Publication
divination
/ˌdɪvɪˈneɪʃ(ə)n/
Origin
late Middle English: from Latin divinatio(n- ), from divinare ‘predict’ (see divine).
/ˌdɪvɪˈneɪʃ(ə)n/
Origin
late Middle English: from Latin divinatio(n- ), from divinare ‘predict’ (see divine).
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The Mac
@TheMac
13 February, 03:13
In response The Mac to his Publication
di-
/dʌɪ,di/
Origin
from Greek dis ‘twice’.
/dʌɪ,di/
Origin
from Greek dis ‘twice’.
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The Mac
@TheMac
13 February, 03:14
In response The Mac to his Publication
From Middle English vīne, from Anglo-Norman vigne, from Vulgar Latin vīnia, from Latin vīnea (“vines in a vineyard”), from vīneus (“related to wine”), from vīnum (“wine”), from Proto-Italic *wīnom, from Proto-Indo-European *wóyh₁nom (“vine, wine”), from *weh₁y- (“to twist, wrap”). Doublet of wine.
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The Mac
@TheMac
13 February, 03:14
In response The Mac to his Publication
In electrodynamics, circular polarization of an electromagnetic wave is a polarization state in which, at each point, the electromagnetic field of the wave has a constant magnitude and is rotating at a constant rate in a plane perpendicular to the direction of the wave.
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The Mac
@TheMac
13 February, 03:16
In response The Mac to his Publication
The electromagnetic spectrum is the range of frequencies (the spectrum) of electromagnetic radiation and their respective wavelengths and photon energies.
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The Mac
@TheMac
13 February, 03:16
In response The Mac to his Publication
Three-phase sinusoids in RGB channels.
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The Mac
@TheMac
13 February, 03:18
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 03:21
In response The Mac to his Publication
A quark (/kwɔːrk, kwɑːrk/) is a type of elementary particle and a fundamental constituent of matter. Quarks combine to form composite particles called hadrons, the most stable of which are protons and neutrons, the components of atomic nuclei.[1] All commonly observable matter is composed of up quarks, down quarks and electrons. Owing to a phenomenon known as color confinement, quarks are never found in isolation; they can be found only within hadrons, which include baryons (such as protons and neutrons) and mesons, or in quark–gluon plasmas.[2][3][nb 1] For this reason, much of what is known about quarks has been drawn from observations of hadrons.
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The Mac
@TheMac
13 February, 03:35
In response The Mac to his Publication
The orbital angular momentum of light (OAM) is the component of angular momentum of a light beam that is dependent on the field spatial distribution, and not on the polarization. It can be further split into an internal and an external OAM. The internal OAM is an origin-independent angular momentum of a light beam that can be associated with a helical or twisted wavefront. The external OAM is the origin-dependent angular momentum that can be obtained as cross product of the light beam position (center of the beam) and its total linear momentum.
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The Mac
@TheMac
13 February, 03:36
In response The Mac to his Publication
Interference of light is the phenomena of multiple light waves interfering with one another under certain circumstances, causing the combined amplitudes of the waves to either increase or decrease.
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The Mac
@TheMac
13 February, 03:37
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 03:56
In response The Mac to his Publication
In fluid dynamics, a Mach wave is a pressure wave traveling with the speed of sound caused by a slight change of pressure added to a compressible flow. These weak waves can combine in supersonic flow to become a shock wave if sufficient Mach waves are present at any location. Such a shock wave is called a Mach stem or Mach front.
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The Mac
@TheMac
13 February, 04:17
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 04:17
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 04:19
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 04:19
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 04:19
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 04:20
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 04:23
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 04:23
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 04:25
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 04:28
In response The Mac to his Publication
The Lighthouse of Alexandria, sometimes called the Pharos of Alexandria (/ˈfɛərɒs/; Ancient Greek: ὁ Φάρος τῆς Ἀλεξανδρείας, contemporary Koine Greek pronunciation: [ho pʰá.ros tɛ̂ːs a.lek.sandrěːaːs]), was a lighthouse built by the Greek Ptolemaic Kingdom of Ancient Egypt, during the reign of Ptolemy II Philadelphus (280–247 BC) It has been estimated to have been at least 100 metres (330 ft) in overall height. One of the Seven Wonders of the Ancient World, for many centuries it was one of the tallest man-made structures in the world.
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The Mac
@TheMac
13 February, 04:31
In response The Mac to his Publication
From Middle English pharao (also as pharaon, farao, faraon, etc.), from Old English pharao, from Late Latin Pharaō, from Ancient Greek Φαραώ (Pharaṓ), from Hebrew פַּרְעֹה (par‘ōh), from Egyptian pr ꜥꜣ (“palace, pharaoh”, literally “pr (“house”) + ꜥꜣ (“great, big”)”).
Pronunciation
(UK, General Australian) IPA(key): /ˈfɛːɹəʊ/, /ˈfɛəɹəʊ/
Audio (UK)
(file)
(US) IPA(key): /ˈfæɹoʊ/, /ˈfɛ(ə)ɹoʊ/
Homophones: faro, Faroe
Noun
pharaoh (countable and uncountable, plural pharaohs)
(historical) The supreme ruler of Ancient Egypt; a formal address for the sovereign seat of power as personified by the 'king' in an institutional role of Horus son of Osiris; often used by metonymy for Ancient Egyptian sovereignty
Pronunciation
(UK, General Australian) IPA(key): /ˈfɛːɹəʊ/, /ˈfɛəɹəʊ/
Audio (UK)
(file)
(US) IPA(key): /ˈfæɹoʊ/, /ˈfɛ(ə)ɹoʊ/
Homophones: faro, Faroe
Noun
pharaoh (countable and uncountable, plural pharaohs)
(historical) The supreme ruler of Ancient Egypt; a formal address for the sovereign seat of power as personified by the 'king' in an institutional role of Horus son of Osiris; often used by metonymy for Ancient Egyptian sovereignty
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The Mac
@TheMac
13 February, 04:35
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 04:38
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 04:40
In response The Mac to his Publication
An ion-dipole force is an attractive force that results from the electrostatic attraction between an ion and a neutral molecule that has a dipole. Most commonly found in solutions. ... A positive ion (cation) attracts the partially negative end of a neutral polar molecule.
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The Mac
@TheMac
13 February, 04:41
In response The Mac to his Publication
The Ionosphere is part of Earth's upper atmosphere, between 80 and about 600 km where Extreme UltraViolet (EUV) and x-ray solar radiation ionizes the atoms and molecules thus creating a layer of electrons. the ionosphere is important because it reflects and modifies radio waves used for communication and navigation.
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The Mac
@TheMac
13 February, 04:42
In response The Mac to his Publication
When an electron is hit by a photon of light, it absorbs the quanta of energy the photon was carrying and moves to a higher energy state. ... So the electron moves to a different orbital where once again its own wavelength is in phase with its self.
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The Mac
@TheMac
13 February, 04:45
In response The Mac to his Publication
The electron electric dipole moment (EDM) de is an intrinsic property of an electron such that the potential energy is linearly related to the strength of the electric field: The electron's EDM must be collinear with the direction of the electron's magnetic moment (spin).
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The Mac
@TheMac
13 February, 04:51
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 04:52
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 04:52
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 04:52
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 04:53
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 04:53
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 04:58
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 04:59
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 05:03
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 05:03
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 05:04
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 05:04
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 05:05
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 05:05
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 05:06
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 05:06
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 05:06
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 05:06
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 05:07
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 05:07
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 05:07
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 05:08
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 05:08
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 05:09
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 05:09
In response The Mac to his Publication
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Only people mentioned by TheMac in this post can reply
The Mac
@TheMac
13 February, 05:10
In response The Mac to his Publication
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The Mac
@TheMac
13 February, 05:11
In response The Mac to his Publication
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