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MARINE_LEO_ Mom
@MarineLEOMom
12 February, 05:20
In response mars 1776 to his Publication
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The Mac
@TheMac
13 February, 05:47
In response MARINE_LEO_ Mom to her Publication
Le-Qing Wu and David Dickman from the Baylor College of Medicine have found neurons in a pigeon's brain that encode the properties of a magnetic field. They buzz in different ways depending on how strong the field is, and which direction it's pointing in.
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The Mac
@TheMac
13 February, 07:09
In response The Mac to his Publication
We show that the artificial field through an attached magnet will quickly disrupt the birds' ability to distinguish pole-ward from equator-ward headings, but that much stronger fields are necessary to disrupt their ability to detect the magnetic axis.
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The Mac
@TheMac
13 February, 07:10
In response The Mac to his Publication
We may finally know the secret to how migrating birds can sense Earth's magnetic fields: a molecule in their eyes called cryptochrome 4 that is sensitive to magnetism, potentially giving the animals an internal compass.
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The Mac
@TheMac
13 February, 07:14
In response The Mac to his Publication
Magnetoreception (also magnetoception) is a sense which allows an organism to detect a magnetic field to perceive direction, altitude or location. This sensory modality is used by a range of animals for orientation and navigation,[1] and as a method for animals to develop regional maps. In navigation, like in bird migration, magnetoreception deals with the detection of the Earth's magnetic field.
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The Mac
@TheMac
13 February, 07:14
In response The Mac to his Publication
Magnetoreception is present in bacteria, arthropods, molluscs, and members of all major taxonomic groups of vertebrates.[1] Humans are not thought to have a magnetic sense, but there is a protein (a cryptochrome) in the eye which could serve this function.[2]
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Edmun Whaley
@Rooffox
13 February, 07:16
In response The Mac to his Publication
thank you for being there
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The Mac
@TheMac
13 February, 07:18
In response Edmun Whaley to his Publication
Wild-Type Mac
Leptoshpaeria schematic
Leptosphaeria rhodopsin (Mac) is a blue-green light-activated proton pump derived from the fungus Leptosphaeria maculans. Mac and its variants allow for inhibition of neurons using blue-green light.
Mac Variants. Mac variants have been engineered to include enhancements such as:
Improved photocurrent amplitude
Example: eMac3.0
😉👍🏻
Leptoshpaeria schematic
Leptosphaeria rhodopsin (Mac) is a blue-green light-activated proton pump derived from the fungus Leptosphaeria maculans. Mac and its variants allow for inhibition of neurons using blue-green light.
Mac Variants. Mac variants have been engineered to include enhancements such as:
Improved photocurrent amplitude
Example: eMac3.0
😉👍🏻
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Edmun Whaley
@Rooffox
13 February, 07:24
In response The Mac to his Publication
excellent name
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Gene Therapy and Light-Sensing Protein Restores Vision in Mice
Using gene therapy, a newly developed light-sensing protein called the MCO1 opsin restores vision in blind mice when attached to retina bipolar cells.
https://www.genengnews.com/news/gene-therapy-and-light-sensing-protein-restores-vision-in-mice/
08:46 AM - Feb 13, 2022
In response Edmun Whaley to his Publication
Only people mentioned by TheMac in this post can reply
The Mac
@TheMac
13 February, 08:47
In response The Mac to his Publication
Here, we report AAV2 assisted delivery of highly photosensitive multi-characteristic opsin (MCO1) into ON-bipolar cells of mice with retinal degeneration to allow activation by ambient light,” write the investigators.
“Rigorous characterization of delivery efficacy by different doses of AAV2 carrying MCO1 (vMCO1) into targeted cells showed durable expression over 6 months after delivery as measured by reporter expression.
“Rigorous characterization of delivery efficacy by different doses of AAV2 carrying MCO1 (vMCO1) into targeted cells showed durable expression over 6 months after delivery as measured by reporter expression.
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The Mac
@TheMac
13 February, 08:48
In response The Mac to his Publication
COVID-19 Vaccine, AAVCOVID | Mass. Eye and Ear
Development of gene-based COVID-19 vaccine, AAVCOVID, underway at Massachusetts Eye and Ear and Massachusetts General Hospital.
https://masseyeandear.org/covid-19/vaccineNotice: Undefined index: tg1tga_access in /home/admin/www/anonup.com/themes/default/apps/timeline/post.phtml on line 396
