Multiple sclerosis (MS), also known as encephalomyelitis disseminate, is a potentially disabling neurodegenerative disease. In MS, the immune system attacks the protective sheath (myelin) that covers nerve fibers and causes communication problems between your brain and the rest of your body. Eventually, the disease can cause permanent damage or deterioration of the nerves.

Signs and symptoms of MS vary widely and depend on the amount of nerve damage and which nerves are affected. Specific symptoms can include double vision, blindness in one eye, muscle weakness and trouble with sensation or coordination. https://reagents.creative-...

Antibody development is the entire process of generating and characterizing an antibody. It starts with injecting an antigen of interest into laboratory animals, allowing the immune system to develop large quantities of antibodies.

Our antibody development and screening services can provide multiple types of antibodies according to your needs. we are able to generate a large number of diverse, high-affinity antibodies towards your target antigen with industry-leading turnaround times and competitive pricing. https://www.creative-diagn...

Creative Diagnostics is striving to develop high-quality detection reagents to support the development of antibiotic detection. After years of research and experience by our technicians, we successfully developed a series of antigens and antibodies for immunoassays, and established the enzyme-linked immunosorbent assay (ELISA) and lateral flow immunoassay (LFIA) detection platforms. https://www.creative-diagn...

The large number of protein impurities generated by cell expression systems is a challenge in biopharmaceutical manufacturing processes. These proteins, called HCP, must be removed during the product purification process or they may compromise the safety and efficacy of the biologic.

Comprehensive and accurate sample characterization and complementary analysis using orthogonal methods are key to HCP detection and removal. Creative Diagnostics provides two-dimensional characterization methods for HCP samples and complement immunoassays for HCP with a range of orthogonal methods, equipping our customers with advanced equipment and experienced researchers for reliable HCP monitoring.
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The measurement is usually carried out on planktonic bacteria (free floating). The MIC value can be determined based on the optical density based on the use of a spectrophotometer or disk diffusion method. This is a time and cost saving strategy for screening and identifying promising drug candidates. The assay can also be adjusted to determine the minimum test concentration required to inhibit the growth of a group of test isolates (MIC50 and MIC90) that are 50% or 90%. https://antiviral.creative...

Given all respiratory illnesses share some similar symptoms, it is not possible to identify the source of an infection based on clinical presentation alone. Combo rapid antigen tests for COVID-19, Flu A/B and RSV can provide with quick, accurate detection within a single test. Creative Diagnostics has several highly sensitive pairs for SARS-CoV-2, Flu A, Flu B and RSV that are ideal for use in a combo rapid COVID-19 assay. In addition, its antibody pair for SARS-CoV-2 is capable of detection of the new highly transmissible Omicron BA.2 variants. https://www.creative-diagn...

Creative Diagnostics is striving to develop high-quality detection reagents to support the development of antibiotic detection. After years of research and experience by our technicians, we successfully developed a series of antigens and antibodies for immunoassays, and established the enzyme-linked immunosorbent assay (ELISA) and lateral flow immunoassay (LFIA) detection platforms. https://www.creative-diagn...

HAI is closely related to HA analysis, mainly through antiviral antibodies as "inhibitors" that interfere with the interaction of viruses and RBCs. The purpose is to characterize the concentration of antibodies in antiserum or other samples containing antibodies. HAI assay is usually performed by creating antiserum dilutions serially in each well of a 96-well microtiter plate. A standard amount of virus or bacteria will be added to each well, and the mixture will be incubated at room temperature. It is necessary to set up a negative control without adding virus for each sample. During the incubation, the antibody will bind to the virus particles. If the antibody concentration and its binding affinity are sufficiently high, the blood coagulation reaction can be effectively blocked. https://antiviral.creative...

Rabies is a fatal zoonotic disease of serious public health and economic significance worldwide. The rabies virus glycoprotein (RVG) has been the major target for subunit vaccine development, since it harbors domains responsible for induction of virus-neutralizing antibodies, infectivity, and neurovirulence. https://www.creative-diagn...

Parathyroid Hormone (pTH) (1-34), is a peptide fragment of the naturally occurring human parathyroid hormone and is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney. It is an important regulator of calcium and phosphorus metabolism, playing a role in calcium homeostasis of bone, kidney, breast, and placenta. pTH (1-34) administration suppresses cardiovascular calcification and down-regulates aortic osteogenic programs driven by diabetes and dyslipidemia. This ELISA was developed with serum from rabbits immunized with pTH (1-34) coupled to a carrier protein.
Immunogen: Synthetic peptide: H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH (Disulfide bond) coupled to carrier protein. https://www.creative-diagn...

High level of GDF-15 has critical role in development and progression of cardiovascular diseases such as heart failure (HF), coronary artery diseases, atrial fibrillation, diabetes, and cancer. Elevated GDF-15 level is a significant feature of cancers including breast, colon, pancreas, and prostate.Thus, GDF-15 measurement aids the diagnosis and management of cancer. https://www.creative-diagn...

The classic method for monitoring HCP impurities in biological products is ELISA, a method that obtains anti-HCP antibodies from animal immunizations, a key component of the assay, and it is critical to ensure that the antibodies used for ELISA cover as much of the HCP in the product as possible. Creative Diagnostics provides HCP coverage assay service that enables the detection and quantification of very low levels of HCP using a combination of immunoaffinity chromatography (IAC) and 2D DIGE analysis, which provides a comprehensive, detailed and efficient determination of ELISA HCP antibody coverage. https://qbd.creative-diagn...

Tick-borne Encephalitis Virus antibodies can be used for applications including neutralization assay and ELISA. Please use the filters to sort the attributes in the table below in order to find the antibody that fits your exact requirements. Our proprietary cloning platform allows us to produce high-quality recombinant versions of these antibodies which will be valuable reagents for research and diagnostics. If you need any further assistance, please do not hesitate to contact us. https://antiviral.creative...

Suid Herpesvirus antibodies can be used for applications including neutralization assay and ELISA. Please use the filters to sort the attributes in the table below in order to find the antibody that fits your exact requirements. Our proprietary cloning platform allows us to produce high-quality recombinant versions of these antibodies which will be valuable reagents for research and diagnostics. If you need any further assistance, please do not hesitate to contact us. https://antiviral.creative...

Anti-tetanus immunoglobulin, also known as tetanus immune globulin (TIG) and tetanus antitoxin, is manufactured from Human plasma. It contains antibodies against tetanus toxoid and is primarily used as prophylaxis against tetanus in wounded patients. Tetanus immune globulin works by giving your body the antibodies it needs to protect it against tetanus infection. https://reagents.creative-...

The human parainfluenza virus (HPIV) is an enveloped, negative-sense, single-stranded RNA virus that belongs to the family of Paramyxoviridae. It is genetically and antigenically divided into four main serotypes, numbered as HPIV-1 to HPIV-4, with further subtypes of HPIV-4a and HPIV-4b.The human parainfluenza viruses 1 and 3 belong to the genus of Respirovirus, and the genus Rubulavirus includes HPIV-2 and 4.HPIV-1 to HPIV-3 are one of the leading causes of lower respiratory infections in infants, young children, adults, the immunocompromised, and the elderly. It is one of the major causes of morbidity and mortality in infants worldwide. https://www.creative-diagn...

Creative Diagnostics is striving to develop high-quality detection reagents to support the development of sedative detection. After years of research and experience by our technicians, we successfully developed a series of antigens and antibodies for immunoassays, and established the enzyme-linked immunosorbent assay (ELISA) and lateral flow immunoassay (LFIA) detection platforms. https://www.creative-diagn...

Creative Diagnostics is striving to develop high-quality detection reagents to support the development of vitamin detection. After years of research and experience by our technicians, we successfully developed a series of antigens and antibodies for immunoassays, and established the enzyme-linked immunosorbent assay (ELISA) and lateral flow immunoassay (LFIA) detection platforms. https://www.creative-diagn...

Rubella Virus (RuV) antibodies can be used for applications including neutralization assay and ELISA. Please use the filters to sort the attributes in the table below in order to find the antibody that fits your exact requirements. Our proprietary cloning platform allows us to produce high-quality recombinant versions of these antibodies which will be valuable reagents for research and diagnostics. If you need any further assistance, please do not hesitate to contact us. https://antiviral.creative...

Rotavirus antibodies can be used for applications including neutralization assay and ELISA. Please use the filters to sort the attributes in the table below in order to find the antibody that fits your exact requirements. Our proprietary cloning platform allows us to produce high-quality recombinant versions of these antibodies which will be valuable reagents for research and diagnostics. If you need any further assistance, please do not hesitate to contact us. https://antiviral.creative...

Ross River Virus antibodies can be used for applications including neutralization assay and ELISA. Please use the filters to sort the attributes in the table below in order to find the antibody that fits your exact requirements. Our proprietary cloning platform allows us to produce high-quality recombinant versions of these antibodies which will be valuable reagents for research and diagnostics. If you need any further assistance, please do not hesitate to contact us. https://antiviral.creative...

Single-cell suspension is required for flow cytometry assays. Thus the adherent cell lines and tissue samples require processing into single-cell suspension before flow cytometry analyzed. A number of protocols are available and involved in mechanical dissociation or enzymatic digestion of the sample. https://www.creative-diagn...

Tetanospasmin is synthesized as a single 151-kDa chain that is cleaved extracellularly by a bacterial protease into a 100-kDa heavy chain and a 50-kDa light chain (fragment A), which remain connected by a disulfide bridge. The heavy chain can be further divided into fragments B and C by pepsin. The heavy chain appears to mediate binding to cell surface receptors and transport proteins, whereas the light chain produces the presynaptic inhibition of transmitter release that produces clinical tetanus. https://www.creative-diagn...

The agents of Marijuana that cause various biological effects in humans are called cannabinoid. Cannabinoid is a central nervous stimulant that alters mood and sensory perceptions, produces loss of coordination, impairs short term memory, produces symptoms of anxiety, paranoia, depression, confusion, hallucination, and increased heart rate. Large doses of cannabinoid could cause the development of tolerances and physiological dependency and lead to abuse. A tolerance to the cardiac and psychotropic effects can occur and withdrawal syndrome produces restlessness, insomnia, anorexia and nausea. Δ9-THC is the primary active ingredient in cannabinoids. https://www.creative-diagn...

Our range of NeutraAbTM Human Papillomavirus (HPV) antibodies can be used for applications including neutralization assay and ELISA. Please use the filters to sort the attributes in the table below in order to find the antibody that fits your exact requirements. Our proprietary cloning platform allows us to produce high-quality recombinant versions of these antibodies which will be valuable reagents for research and diagnostics. If you need any further assistance, please do not hesitate to contact us. https://antiviral.creative...

Our range of NeutraAb™ Human Immunodeficiency Virus (HIV) antibodies can be used for applications including neutralization assay and ELISA. Please use the filters to sort the attributes in the table below in order to find the antibody that fits your exact requirements. Our proprietary cloning platform allows us to produce high-quality recombinant versions of these antibodies which will be valuable reagents for research and diagnostics. If you need any further assistance, please do not hesitate to contact us. https://antiviral.creative...

Our range of NeutraA™ Human Herpesvirus antibodies can be used for applications including neutralization assay and ELISA. Please use the filters to sort the attributes in the table below in order to find the antibody that fits your exact requirements. Our proprietary cloning platform allows us to produce high-quality recombinant versions of these antibodies which will be valuable reagents for research and diagnostics. If you need any further assistance, please do not hesitate to contact us. https://antiviral.creative...

The Human Diphtheria Toxoid IgG Antibody ELISA Test Kit has been designed for the detection and the quantitative determination of specific IgG antibodies against Diphtheria Toxoid in serum and plasma. https://reagents.creative-...

Human uPA ELISA Kit
For quantitative detection of PLAU/uPA in serum, plasma, tissue homogenates and other biological fluids.
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This human antithrombin III antigen assay is intended for the quantitative determination of total antithrombin III antigen in human plasma. For research use only. https://reagents.creative-...