Up to now, various methods have been developed for quantifying cellular levels of dNTPs, including enzymatic and liquid chromatography assays. The latter involves direct separation of dNTPs by high-performance liquid chromatography (HPLC), which can be detected using UV or tandem mass spectrometry. Ideally, a combination of these two methods should be used for sensitive and reliable quantification. Similarly, the identification and quantification of cyclic-di-AMP would be more effectively achieved through the utilization of LC-MS/MS. With integrated set of separation, characterization, identification, and quantification systems featured with excellent robustness & reproducibility, high sensitivity, Creative Proteomics provides reliable, rapid, and cost-effective deoxynucleotide triphosphates (dNTPs) and cyclic-di-AMP targeted metabolomics services. https://www.creative-prote...
05:03 AM - Mar 26, 2024
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