Powerful approaches have become more accessible that allow the profiling of rare or heterogeneous populations of cells. The averaging that occurs in Conventional 'bulk' methods of sequencing does not allow the direct assessment of the fundamental biological unit—the cell—or the individual nuclei that package the genome. CD genomics provides access to the genomic and genetic analysis at single cell level using 10x genomics system and its engineered reagent delivery method. The droplet-based platforms Chromium 10x System, powered by GemCode Technology, enables the biomedical researchers and clinicians to make important new discoveries using this powerful approach as the technologies and tools needed for conducting single cell studies. Moreover, the droplet-based platforms, maximizing the throughput of cells and meanwhile downscaling the reactions to nanoliter volumes, has been shown to improve detection sensitivity and quantitative accuracy. The droplet-based methods hold advantages, all