CD Genomics provides bacterial de novo sequencing data analysis. Using bioinformatics to explore the whole genome sequence map of bacteria in one step, our unique data analysis skills and advanced software tools can meet our customers' personalized data analysis needs and provide you with easy-to-interpret data analysis reports. https://bioinfo.cd-genomic...

As one of the group evolution analysis providers, CD Genomics uses bioinformatics to help you analyze the population information and reveal the process of population evolution quickly and accurately. Our unique data analysis skills can meet customers' personalized data analysis needs and provide the most easy-to-interpret data analysis reports. https://bioinfo.cd-genomic...

CD Genomics provides a battery of biofluid profiling services utilizing next-generation sequencing technology. Our services can complement mainstream sequencing methods to investigate the levels of RNA molecules in biofluid samples, explore poorly characterized, rare transcripts and mutations. Cell-free RNA sequencing (RNA-seq) is a tool that extracts, processes, and analyzes cell-free RNA. We have developed a complete, automated workflow for performing cell-free RNA-seq. Our services are fully customizable to your research needs. https://rna.cd-genomics.co...

Next-generation sequencing (NGS)-based methods, either relying on antibody enrichment or third-generation sequencing, have been developed to map post-transcriptional RNA modification and explore their functions, We provide a full range of epitranscriptomics services to investigate RNA modifications using NGS or long-read sequencing (Oxford nanopore sequencing and PacBio SMRT sequencing). We can help you detect many forms of RNA modifications including m7G, m3C, m1A, 5mC, 5hmC, m6A, m6Am, acetylation, and 2'-O-methylation. https://rna.cd-genomics.co...

Viral metagenomic studies have provided insights into viral ecology by elucidating the genetic potential, community structure, and biogeography of environmental viruses. Viral metagenomics has expanded current knowledge on virus-host interactions by uncovering genes that may allow the viruses to manipulate their hosts in unexpected ways. The intrinsic potential for virus discovery through viral metagenomics can help advance a wide array of disciplines including evolutionary biology, pathogen surveillance, and biotechnology. In addition, functional viral metagenomics serves as a platform to discover more useful enzymes. As the annotation of viral genes continues to improve, the discovery of vital enzymes will increase considerably. https://www.cd-genomics.co...

Fungi, a large group of eukaryotes, consist of microorganisms such as yeast and mold, as well as the mushrooms. Many beneficial fungi have important nutritional and medicinal value. However, some pathogenic fungi can cause disease in humans, animals, or plants. With the maturity of high-throughput sequencing technologies, the cost of genome sequencing has been greatly reduced, making it possible to sequence fungal genomes quickly and economically. Fungal whole genome sequencing allows us to obtain the genome sequence of fungi and study their structure and function. https://www.cd-genomics.co...

Long-read sequencing technologies, including PacBio SMRT and Oxford Nanopore sequencing, make it possible to detect variants in genomic regions that are proposed difficult to map through typical short-read sequencing methods (such as Illumina sequencing). CD Genomics is a leading global life sciences company. We specialize in the application of third-generation sequencing technologies. With the help of our advanced platform and skilled experts, researchers can detect all variant types from long-read datasets and discover new variants in complex genomic regions. https://longseq.cd-genomic...

CD Genomics is a leading provider of genomic services. We have extensive experience in long-read amplicon sequencing using the PacBio platform. PacBio SMRT long-read sequencing is capable of generating complete, uniform, unbiased coverage spanning long amplicons, allowing for a more realistic restoration of the microbial community structure in the samples. 16S/18S/ITS amplicon sequencing, also known as microbial diversity sequencing, refers to the sequencing of PCR products from specific regions such as 16S ribosomal DNA (rDNA), 18S rDNA, Internal Transcribed Spacer (ITS), and functional genes. This method does not require culturing microorganisms, and by detecting sequence variation and abundance in the target region, information on microbial community structure, evolutionary relationships, and microbial relevance to the environment can be obtained from environmental samples. https://www.cd-genomics.co...

The identification of microorganisms has relied on phenotypic methods at early eras. With advances in genetic methods, various classification methodologies based on nucleotide sequences are increasingly popular due to their specificity and speed. Gene sequencing-based techniques can serve to detect, identify, and monitor microbes, even poorly known or uncultured microorganisms. https://www.cd-genomics.co...

CD Genomics is proud to provide genotyping by sequencing service to advance your population based genotyping studies in an effective and economic way. Please contact us for more information and a detailed quote. CD Genomics is the licensed service provider for this technology. Keygene N.V. owns patents and patent applications protecting its Sequence Based Genotyping technologies. https://www.cd-genomics.co...

A series of studies have confirmed that T-cell receptor (TCR) repertoire could sever as a biomarker for monitoring immune response. CD Genomics has developed a state-of-the-art high throughput sequencing method (TCR-Seq) to characterize the TCR repertoires. TCR, which locates on the surface of T cells, is responsible for the recognition of the Ag-MHC (major histocompatibility complex) molecules. The recombination of the variable (V), diversity (D), and joining (J) genes generates the immense diversity of TCR, which is critical to the adaptive immune system. In this way, the sequencing and analysis of TCR repertoire may help to obtain a better understanding of the response of adaptive immunity, and ultimately, sheds light on the discovery of novel infectious agents and holds the invaluable potential to aid in antibody or vaccine development, clinical diagnosis, treatment, and prevention. https://www.cd-genomics.co...

Genotyping helps determine differences in the individual's genetic makeup, such as single nucleotide polymorphisms (SNPs) and large structural changes in DNA. Genotyping analysis plays an important role in research of genes and gene variants associated with disease. Next-generation sequencing (NGS) and microarrays enable a deeper understanding of disease etiology on a molecular level. With multiple genomic targets potentially contributing to disease, analysis requires flexibility and accuracy. SNP genotyping and copy number variation (CNV) data analysis tools can analyze results for millions of markers and probes and detect sample outliers, providing insight into the functional consequences of genetic variation. SNP genotyping is also used in many scientific disciplines including personalized medicine, plant and animal biotechnology. https://bioinfo.cd-genomic...

In genetics, a genome-wide association study (GWAS) is an observational study of a genome-wide set of genetic variants in different individuals to investigate whether any variant is associated with a trait. GWASs typically focus on associations between single-nucleotide polymorphisms (SNPs) and traits like major human diseases, but can equally be applied to any other genetic variants and any other organisms. As one of the providers of genome-wide association analysis, CD Genomics uses bioinformatics to help you achieve efficient mapping of multiple target trait genes quickly and accurately. Our unique data analysis skills can meet customers' personalized data analysis needs and provide easy-to-interpret data analysis reports. https://bioinfo.cd-genomic...

CD Genomics not only provides comprehensive short-read and long-read sequencing services, but also has a professional bioinformatics team to guide the analysis solutions of genomic, transcriptomic and epigenomic metadata. We provide session analysis services not limited to sequencing data quality control, annotation, alternative splicing analysis, assessment, differential expression analysis, regulatory interaction network, and functional analysis. We are experienced in helping to analyze abiotic and biotic stress, developmental stages, therapeutic and other bioinformatics analysis and genome data mining. We deliver the complete report of methods, tools, visualization analysis results and all other reports in a secure and confidential service process. https://rna.cd-genomics.co...

MicroRNAs (miRNAs) are key regulators of gene expression and their dysregulation has been associated with various diseases. Understanding the interactions between miRNAs and messenger RNAs (mRNAs) is crucial for unraveling gene regulatory networks and discovering diagnostic and prognostic markers. CD Genomics offers a comprehensive miRNA-mRNA interaction analysis service to investigate these relationships using deep sequencing and advanced bioinformatics techniques. https://rna.cd-genomics.co...

Tag-Seq is a high-throughput sequencing approach that is primarily used for characterizing gene expression levels and identifying novel transcripts. The data generated by the service can be useful for a wide range of applications, including gene expression studies, biomarker discovery, and transcriptome annotation. https://rna.cd-genomics.co...

DNA methylation also contributes to cellular differentiation and development of organisms, which is crucial to understand gene expression and silencing in the development of cancer and other diseases. Microbial epigenomics provides insight into important tumorigenic pathways and enables us to find the molecular markers in multiple biological processes and understand underlying mechanisms associated with complex diseases. Microbial epigenomics analysis can be used in many areas of research, including cell cycle control, DNA repair, developmental biology, cancer research, and discovery of potential biomarkers and drug targets. https://www.cd-genomics.co...

Multi-locus sequence typing (MLST) is a molecular biology method with high resolution based on the analysis of internal fragments of multiple housekeeping genes by PCR and sequencing. It can be used to identify and classify unidentified bacterial and fungal organisms at the species and strain levels. It has been applied in both molecular epidemiological studies and molecular evolution analysis. We provide MLST service to help you characterize isolates of microbial species and to accelerate studies of SNPs, resistance genes, and virulence factors of strains. https://www.cd-genomics.co...

CD Genomics' single molecule, real-time sequencing (SMRT)-based microbial targeted and whole-genome sequencing services can help you with precise microbial identification, generation of complete reference genomes, comparative genomic studies, and genomic exploitation. The applications for SMRT-based genome sequencing vary. Just to list a few: accurate microbial identification, microbial genomic characterization, pathogen detection, environmental monitoring, and routine testing of raw materials for bacterial contamination. https://www.cd-genomics.co...

To address the emerging needs of research communities, CD Genomics has developed an affordable, reliable, and high-throughput strategy for CRISPR Screen sequencing by harnessing amplicon based next-generation sequencing. Our CRISPR Screen sequencing service can give you direct and detailed information about sgRNA and targeted gene analysis and functional enrichment analysis, to help researchers study genes functions in a high-throughput fashion." https://www.cd-genomics.co...

CD Genomics provides fungal whole genome sequencing with the PacBio Sequel system to offer more insights into genetic structure and functions. We are best in the knowledge, practice, and experience. Fungi play vital roles in the biosphere and are closely related to human life with important medical and economic value. Fungi are involved in a wide range of activities—some fungi are decomposers, parasites or pathogens of other organisms, and others are beneficial partners in symbiosis with animals, plants or algae. Some fungi affect human health in various ways. Fungi are also the major sources of antibiotics, such as penicillin from the fungus Penicillium. https://www.cd-genomics.co...

CD Genomics is now able to provide Assay for Transposase-Accessible Chromatin with high-throughput sequencing (ATAC-seq), a method for mapping chromatin accessibility genome-wide. The method is a fast and sensitive alternative to DNase-seq (DNase I hypersensitive sites sequencing) or MNase-seq (micrococcal nuclease sensitive sites sequencing). By using our service, you can detect genome-wide profiles of open and accessible regions of chromatin that are indicative of active regulatory regions. https://www.cd-genomics.co...

CD Genomics's mRNA-Seq service, powered by the state-of-the-art Illumina NovaSeq platforms, offers comprehensive solutions for gene expression quantification, differential gene expression analysis, identification of novel transcript isoforms, alternative splicing, and gene fusions, etc. Our expert team works closely with you to provide standard and customized high-throughput sequencing and bioinformatics analyses based on project-specific needs, as well as exquisite results for publication. https://rna.cd-genomics.co...

CD Genomics provides Iso-Seq service, an end-to-end solution for direct sequencing and analysis of full-length transcript isoforms, avoiding the need for transcript reconstruction and inference, and enabling discovery of novel transcripts and genes, functional characterization of isoforms and alternative splicing (AS) events, and identification of fusion genes. Please contact our expert team to discuss how our Iso-Seq service can refine your NGS projects. https://rna.cd-genomics.co...

"CD Genomics uses a mature high-throughput sequencing platform combined with epigenetics to provide a variety of biological information analysis services, such as genome-wide epigenetic positioning analysis and genes research on expression regulation mechanism. We will provide you with a clear and reliable report of epigenetic analysis result.
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In the process of transcriptomic research, the main purpose of our high-throughput sequencing is to find genes expressed differentially and explore the possible functions of these genes. For example, comparing the tissue expression profiles of diseased and normal individuals, it is reasonable to expect that the genes showing significant differences are related to the occurrence of diseases. These genes may be involved in immune-related biological processes, signal pathways, and gene expression levels. Therefore, after identifying these genes, the pathways involved are often annotated. Through GO or KEGG enrichment analysis, these differentially expressed genes can be mapped to GO or KEGG classification entries, so as to understand the regulatory pathways involved in these genes, and finally correlate with the phenotype. https://bioinfo.cd-genomic...

icroorganisms were thought to cause serious disease. However, some types of the microorganisms can synthesize biologically active molecules and be used as therapeutics. More pharmaceutical companies have realized the values and directed their clinical development efforts towards microbial therapeutics. The potential of microbial therapeutics is evident in the probiotics and live bacterial prophylactic vaccines, as well as more the recent cases using fecal microbiota transplant to improve human health or cure certain diseases. https://www.cd-genomics.co...

Antibiotic resistance has been a threat to the global health concern. Antibiotic-resistance bacteria can acquire antibiotic resistance genes (ARGs) due to selective pressure. CD Genomics is offering efficient, accurate, genome-based analysis of antibiotic resistance gene screening services, to locate ARGs, identify novel ARGs, and reveal the molecular mechanism underlying ARGs transfer. https://www.cd-genomics.co...

A direct PCR approach is applied to our nanopore-based full-length 16S/18S/ITS sequencing, allowing the direct amplification of 16S/18S/ITS sequences from bacterial/archaeal/fungal/eukaryotic cell suspensions via PCR without DNA purification. This approach overcomes the limitations of the traditional culture-based bacterial identification, instead providing rapid and accurate microbial identification and diversity analysis. https://www.cd-genomics.co...

Long-read RNA-seq can overcome some of the inherent limitations of short-read RNA-seq to improve gene prediction and annotation in genome assembly, ultimately providing full-length RNA sequences and complete structural information. Besides Pacbio RNA sequencing services, CD Genomics also offers Oxford nanopore RNA sequencing services. Nanopore RNA sequencing technology enables accurate analysis of full-length native RNA or cDNA without the need to amplify or fragment, streamlining analysis and eliminating amplification bias and read length limitations. More importantly, it is currently the only technology capable of directly sequencing native RNA strands. Direct sequencing of RNA using nanopore sequencing technology identifies base modifications next to nucleotide sequences, analyzes poly-A tail lengths and transcription start sites, and analyzes full-length isoforms to recover the true RNA characteristics. https://longseq.cd-genomic...