Oxidative stress plays a critical role in nanotoxicity. Various types of nanoparticles are known to induce oxidative stress by generating intracellular reactive oxygen species (ROS). Cellular uptake of nanoparticles and intracellular metal ion release are important factors for intracellular ROS generation. Besides, ROS generation can result from interactions of nanoparticles and cells that lead to mitochondrial dysfunction. In vivo, nanoparticles induce the secretion of cytokines, which, in turn, induce secondary oxidative stress via generation of ROS and free radicals.

Recently, evidence has accrued that a significant proportion of individuals with autism have concomitant diseases such as mitochondrial disease and abnormalities of energy generation. This has therefore led to the hypothesis that autism may be linked to mitochondrial dysfunction.

Yes-as a nurse we call it the cytokine storm...💥