The activation of three pathway results in the formation of the C5 convertase, which in turn cleaves C5 into C5a and C5b to initiate the formation of the terminal complement complex (TCC) at the targeted site sequentially together with C5b, C6, C7, C8 and C9, which is also called as the membrane attack complex (MAC). Assembly of the MAC on target cells results in the formation of transmembrane pores that can lead to the killing of the cells, which is the signature feature of complement. Learn more, https://www.creative-biola...