The significant relationship between changes in kinase levels and activity and physiological and pathological changes in the central nervous system (CNS) underscores the need for CNS-associated cellular kinase analysis as an important focus for the development of personalized medicine research. Creative Biolabs, a global leader in neurological research, is able to provide the most professional services for our clients' CNS-related cellular kinase analysis. https://neuros.creative-bi...

Macrophages are innate immune cells characterized by evolutionarily conserved functions, such as host defense against infection and tissue homeostasis. Macrophages present a high plasticity grade, being able to change their phenotype in response to environmental stimuli. They play central roles during development, homeostatic tissue processes, tissue repair, and immunity. https://macrophage.creativ...

Macrophages are innate immune cells characterized by evolutionarily conserved functions, such as host defense against infection and tissue homeostasis. Macrophages present a high plasticity grade, being able to change their phenotype in response to environmental stimuli. They play central roles during development, homeostatic tissue processes, tissue repair, and immunity. https://macrophage.creativ...

Cardiac diseases are the leading cause of mortality and morbidity worldwide, especially in the elderly. The primary function of the heart is to pump the blood that supplies oxygen and nutrients to the entire body. This association between inflammation and adverse cardiac events is well-acknowledged. Immune response participates in several heart conditions and diseases, including myocardial infarction (MI), myocarditis, endocarditis, myocardial fibrosis (MF) and arrhythmia. Many cardiac diseases have been recognized as inflammatory conditions characterized by the infiltration of monocytes and macrophage differentiation to promote localized inflammation. https://macrophage.creativ...

Recombinant antibodies (rAbs) have been widely applied in the field of biological research, diagnosis and therapy based on their unique advantages. Without immunization and screening process, antibody gene sequence is cloned and expressed in vitro via cellular expression system. Currently, mammalian cells are the preferred system for large-scale production as the rAbs produced are biochemically similar to human forms. https://neutab.creative-bi...

Human beings as the most important research objects in biological research, meanwhile mouse as the most precious tool for biomedical research, antibodies target human and mouse protein individually is an important tool in biological research. With the advanced platform and extensive experience in antibody discovery and development, Creative Biolabs offers several sets of human and mouse antibodies (IgM, IgG or IgA), as well as customized antibody development services to meet global customers’ needs. https://neutab.creative-bi...

Creative Biolabs specializes in antibody discovery, development, and production for virology research. Innovate with world-class equipment and lab facilities supported by our in-house team of professional scientists, we developed a novel pepFastX™ antibody discovery platform. It is a fast antibody screening platform based on a pre-made mouse monoclonal antibody library against peptides derived from millions of proteins across hundreds of species. The mAb products can be delivered within 2-3 months. https://viroantibody.creat...

The rapid emergence of infectious diseases, such as COVID-19, highlights the critical need to better understand the biology of viral infection, host interactions, and the immune response. At Creative Biolabs, we have developed a variety of virology assays to determine the viral titer and assess the effectiveness of antibodies, antivirals, and vaccines. Our expertise provides our clients with the most robust portfolio of assays for their virology research. https://viroantibody.creat...

Standardized neural chips often use a multi-chamber structure. Multiple culture chambers are connected by narrow channels, and the specific growth of axons can be achieved by controlling the height and length of the channels. When the height of the microchannel is less than 5 μm, only neurites can enter the tunnel, and when the length of the microchannel exceeds 400 μm, only axons can extend into another chamber. Learn more, https://microfluidics.crea...

Microfluidic technologies for cell separation in the biomedical field are booming in the recent 15 years. Benefitted from the microscale features approaching a single cell, microfluidic cell sorting devices have shown many attractive advantages compared to their forerunners (e.g., fluorescence-assisted cell sorting (FACS) and magnetic-assisted cell sorting (MACS)). Learn more, https://microfluidics.crea...

DSPE-PEG is a biocompatible polymer used in drug delivery systems. It improves solubility and stability, facilitating targeted therapy. This compound enhances the pharmacokinetics of pharmaceuticals, making it a vital component in nanomedicine and biopharmaceutical applications. Its unique properties enable efficient cellular uptake and reduced toxicity.
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Multi-strain probiotics consist of various beneficial bacteria strains that work synergistically to enhance gut health. These probiotics can improve digestion, boost immunity, and restore the natural balance of gut flora. By incorporating diverse strains, they offer a broader range of health benefits and support overall well-being. https://live-biotherapeuti...

A variety of neurological illnesses are linked to astrocyte dysfunction. Traditional research of astrocytes is based on the limited primary cells or mouse astrocytes. Astrocytes from human pluripotent stem cells are difficult and inefficient. Creative Biolabs, with well-established differentiation platforms, can rapidly and efficiently generate human astrocytes of high quality, regarding morphology, molecule profile, and function. We provide custom astrocyte differentiation services to our clients worldwide to facilitate your research. https://neurost.creative-b...

Creative Biolabs has extensive experience in drug discovery and has successfully accomplished hundreds of projects. We have developed a comprehensive technology platform to provide one-stop CNS drugs discovery services. Our platform has advanced neuroscience ex vivo models, neuroscience assay technique, and neuroscience research tools. These technologies will cover every important stage of CNS drug discovery, resulting in a one-stop shop for our customers. https://neurost.creative-b...

In order to explore more effective treatments, a more complete understanding of the pathophysiology of AD is required. Animal models can reproduce the overt changes occurring in patients with AD. However, complex in vivo conditions may limit the accessibility to the tissue of interest and prevent real-time and spatial measurements of biological changes. Consequently, several in vitro experimental models of AD, which provide detailed regional and cell-level information, have been developed to enhance the usefulness of animal models of alzheimer's disease. https://neuros.creative-bi...

At present, the main research focuses on the β-amyloid (Aβ) and tau protein markers in cerebrospinal fluid (CSF). After decades of accumulation, Creative Biolabs has established an advanced platform for Aβ and tau detection. We are committed to providing professional AD in vitro testing services to customers around the world. https://neuros.creative-bi...

For more than a decade, Creative Biolabs has provided high-quality experimental material needed for different projects to ensure quality research outcomes. Here, we also provide customized 3D cell culture model development services to our clients at the global level to support your project. https://neuros.creative-bi...

Creative Biolabs presents an extensive selection of cutting-edge in vitro assay services focused on neurological diseases. These assays provide a profound understanding of disease mechanisms at the cellular level, aid in drug discovery, and pave the way for personalized therapeutic strategies. https://neuros.creative-bi...

Experienced in macrophage development and with a dedicated commitment to the scientific community, Creative Biolabs has perfected our technical pipelines in the identification of M1 and M2 macrophages. We are happy to share our knowledge and passion in this field to facilitate our clients' research and project development. Learn more, https://macrophage.creativ...

By applying our state-of-the-art Macrophage Therapeutics Development Platform as well as industry-leading expertise, Creative Biolabs provides overall solutions for macrophage reprogramming, focusing on innovative research. Our multidisciplinary scientists will work together closely to address the scientific and technical challenges in macrophage reprogramming. Learn more, https://macrophage.creativ...

Macrophages are able to initiate a particular type of inflammatory response via the release of a certain pattern of cytokines. They play a major role as immunoregulatory cells. Creative Biolabs has built a highly experienced team of scientists and quality staff that have a long history in macrophage isolation and culture. Learn more, https://macrophage.creativ...

As a type of functionally diversified immune cell widely spread throughout the whole body, macrophages play critical roles in the regulation of homeostasis, inflammation, and antitumor immunity in a specific manner. Macrophages are easily transformed into inflammatory (M1) and can also demonstrate effective phagocytosis. The M1 profile is classically associated with the control of bacterial infections. Creative Biolabs offers highly customized assays to induce M1 macrophages and characterize their polarization states. Learn more, https://macrophage.creativ...

Creative Biolabs is dedicated to providing a full range of antibody and peptide discovery services from vector construction to antibody production and antibody efficacy assessment, helping clients discover and develop highly effective and specific anti-infective hits. Learn more, https://www.creative-biola...

Creative Biolabs is actively supporting and assisting clients in exploring and developing the enormous potential of interfering nucleic acid drugs in the treatment of infectious diseases. Learn more, https://www.creative-biola...

The discovery of effective targets to restrict the growth and spread of pathogens is critical to infectious illness treatment. Creative Biolabs provides high-throughput proteomics analysis services that can identify disease-associated proteins, thus helping to discover possible targets for intervention in infections. Learn more, https://www.creative-biola...

Creative Biolabs is dedicated to providing comprehensive solutions for infectious disease research with scalable genomics approaches. Through comprehensive genomic analysis, researchers are able to identify and discover possible targets, monitor host-pathogen interactions, study pathogen evolution and predict the occurrence of drug-resistant genotypes. Learn more, https://www.creative-biola...

https://www.creative-biola... developing various biomarkers or targets to better diagnose or treat non-alcoholic steatohepatitis (NASH), preclinical testing tools are needed for compound screening and mechanical studies. As part of our portfolio of NASH-related services, Creative Biolabs offers customized in vitro-engineered liver model services to study drugs or biomarkers for NASH treatment. Learn more,

Neutralizing Antibodies and Antimicrobial Peptides Targeting S Protein Neutralizing antibodies are induced by antigens to protect cells from pathogen infection. Most neutralizing antibodies function at the earliest steps of viral infection through blocking interaction of the virus with cellular receptors and prevent entry into host cells. It has been reported that RBD of S protein efficiently elicits neutralizing antibodies against MERS-CoV by blocking viral entry at the binding step. Learn more, https://www.creative-biola...

Andes Virus (ANDV), a type of orthohantavirus, belongs to the family Hantaviridae which consists of 5 genera: bunyavirus, phlebovirus, nairovirus, tospovirus, and hantavirus. This virus was first found in rodent at Andes mountains of Chile and Argentina. ANDV infection is a leading cause of hantavirus cardiopulmonary syndrome (HCPS), hantavirus pulmonary syndrome (HPS), and hemorrhagic fever with renal syndrome/failure (HFRS). ANDV maintains persistent apathogenic infections in rodents and is easily transmitted to humans mainly through inhalation of aerosolized rodent excreta or rodent bites, leading to the occurrence of ANDV-infected diseases. Besides, ANDV is the only hantavirus that is capable of person-to-person transmission. Learn more, https://www.creative-biola...

LAG-3 inhibitor plays an important role in T cell proliferation and activation as a negative regulator of these processes. Along with other inhibitory receptors, LAG-3 helps to keep cytotoxic CD8+ T cells in an exhausted state during highly inflammatory environments such as a chronic viral infection. LAG-3 has also been implicated in memory T cell expansion, Treg function, and the activation and maturation of dendritic cells. Learn more, https://immune-checkpoint....