There are several known side effects of barium in the human body. Barium greatly affects those people who work in the barium industry and most of its health risks are caused by breathing in air that contains barium sulfate or barium carbonate. Barium exposure may lead to difficulty in breathing, increased blood pressures, heart rhythm changes, irritation in the stomach, muscle weakness, changes in nerve reflexes, swelling of brains and liver, and kidney and heart damage. Moreover, barium can harm the skin and cause severe skin burns and skin irritation. It can also cause irritation in the eyes and respiratory tract. Barium can also cause vomiting, colic, diarrhea, tremors, and paralysis.

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