by A Schroeder · 2009 · Cited by 420 — Recently, the ability of ultrasound to induce localized and controlled drug release from liposomes, utilizing thermal and/or mechanical effects, has been shown. This review, deals with the interaction of ultrasound with liposomes, focusing mainly on the mechanical mechanism of drug release from liposomes using LFUS.

Among the various particulate delivery systems, liposomes—bubble-like nano/microsized lipidic bilayer structures—have shown great promise as an antigen-carrying vehicle. Few liposomal vaccines have been introduced to the market. The key advantages of liposomes as a vaccine delivery system are their ability to protect antigens against degradation, carry single or multiple hydrophilic and lipophilic antigens, control the release of antigens, enhance cellular uptake, and improve antigen-specific immune responses.