The Mac on AnonUp.com

21 February, 03:10

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The Mac @TheMac

21 February, 04:16

In response Bondservant Mark to his Publication

by Y Mei · 2012 · Cited by 68 · Related articles
4 Apr 2012 — Both lentivirus and adeno- associated virus (AAV) vectors have been used to deliver optogenetic constructs into genetically ...

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The Mac @TheMac

21 February, 04:49

In response The Mac to his Publication

by KA McGuire · 2011 · Cited by 73 · Related articles
We demonstrate that ROS are produced within minutes of adenovirus type 5 (Ad5) infection of macrophages and that oxidative stress supports ...

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The Mac @TheMac

21 February, 04:51

In response The Mac to his Publication

by G Bjørklund · 2020 · Cited by 25 · Related articles
5 Feb 2020 — Children with ASD diagnosis are considered more vulnerable to oxidative stress because of their imbalance in intracellular and ...

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The Mac @TheMac

21 February, 04:55

In response The Mac to his Publication

https://bmcneurosci.biomed...

Optogenetic regulation of transcription | BMC Neuroscience | Full Text

Optogenetics has become widely recognized for its success in real-time control of brain neurons by utilizing non-mammalian photosensitive proteins to open or close membrane channels. Here we review a less well known type of optogenetic constructs that employs photosensitive proteins to transduce the..

https://bmcneurosci.biomedcentral.com/articles/10.1186/s12868-018-0411-6

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The Mac @TheMac

21 February, 04:56

In response The Mac to his Publication

https://www.ncbi.nlm.nih.g...

Principles of Optogenetic Methods and Their Application to Cardiac Experimental Systems

Optogenetic techniques permit studies of excitable tissue through genetically expressed light-gated microbial channels or pumps permitting transmembrane ion movement. Light activation of these proteins modulates cellular excitability with millisecond ...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749684/

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The Mac @TheMac

by EA Ferenczi · 2019 · Cited by 22 · Related articles
11 Sept 2019 — It is also possible to express optogenetic constructs in neonatal and adult primary ventricular cardiomyocytes using viral vector ...

04:57 AM - Feb 21, 2021

In response The Mac to his Publication

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The Mac @TheMac

21 February, 05:00

In response The Mac to his Publication

Of the many viruses screened, adenovirus 36 has been found to be a strong candidate virus that is associated with obesity, based on evidence in various model systems as well as clinical data. The mechanism of how the adenovirus could lead to obesity is not known and this paper proposes some new insights into how oxidative stress could be a possible mechanism of how adenovirus might lead to obesity. This paper reviews the relevant literature of both the effect of adenovirus on cells' anti-oxidant response and the link between obesity and oxidative stress.

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The Mac @TheMac

21 February, 05:04

In response The Mac to his Publication

"Our results suggest that oxidative stress may be partly responsible for the toxicity of adenovirus transduction."

https://jvi.asm.org/conten...

Redox Regulation of Adenovirus-Induced AP-1 Activation by Overexpression of Manganese-Containing Superoxide Dismutase | Journal of Virology

Adenovirus gene therapy is a promising tool in the clinical treatment of many genetic and acquired diseases. However, it has also caused pathogenic effects in organs such as the liver. The redox-sensitive transcription factors AP-1 and NF-κB have been implicated in these effects. To study the mechan..

https://jvi.asm.org/content/76/1/355