Scientists have uncovered a striking new strategy against one of the deadliest brain cancers known to medicine. In laboratory studies, a combination of a commonly used antidepressant and a blood thinning medication forced glioblastoma cells into a destructive biological loop that caused them to consume themselves from within. Glioblastoma is notorious for resisting standard treatments like surgery, radiation, and chemotherapy. Researchers found that when these two existing drugs were used together, they disrupted the cancer cells’ internal survival systems.
05:03 AM - Feb 19, 2026
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Myra Raney
@myralynnr
19 February, 05:03
In response Myra Raney to her Publication
The combination triggered excessive autophagy, a process where cells recycle their own components. While autophagy normally helps cells survive under stress, in this case it went into overdrive and became fatal. At the same time, the drug pairing interfered with iron regulation inside the tumor cells, increasing oxidative stress. This pushed the cells into a form of programmed death linked to iron toxicity. The result was a feedback loop where the cancer cells kept breaking down their own structures until they could no longer survive.
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