Really? How so?

Grapefruit juice can interfere with some medications because it contains chemicals that inhibit enzymes in the digestive system responsible for breaking down certain drugs. This can lead to increased or decreased drug levels in the body, potentially causing adverse reactions or making the medication less effective.
Here's a more detailed explanation:
1. Enzyme Inhibition:
CYP3A4 Enzyme
When CYP3A4 is inhibited, the body cannot break down these drugs as efficiently, leading to higher concentrations of the drug in the bloodstream.
Increased Risk of Side Effects:
This can amplify the drug's effects and increase the risk of side effects, potentially leading to toxicity.
2. Increased or Decreased Bioavailability:
Increased Absorption:
In some cases, grapefruit juice can increase the amount of drug absorbed into the bloodstream, making the medication more potent.
Reduced Absorption