Jesus is the only one permitted to break the seals and open the scroll, so nothing happens without God's permission. Only in His timing. Everything that happens is subject to His direction only. No human can open the scroll. The scroll is fully sealed with 7 seals perfectly until the proper time and the proper person to open the scroll. As each seal is broken, an event happens on the earth, that no man can alter.

John saw the man on the throne holding a scroll in his right hand. The scroll had writing on both sides and was sealed with seven seals. A mighty angel proclaimed in a loud voice, “Who is worthy to break the seals and open the scroll?” No one in heaven or on earth was worthy to open the scroll. John cried because no one was found who was worthy to open the scroll.

Then one of the elders said to John, “Do not weep! The Lion of the tribe of Judah, the Root of David, has triumphed. He is able to break the seven seals and open the scroll.”