How to Construct An iPSC-based Disease Model?

The process of creatingiPSCs from somatic cells (such as fibroblast, blood mononuclear cells, or urine cells from a patient or a healthy individual) is the first step in iPSC-based disease modeling. By applying specific culture conditions, these iPSCs can be differentiated into cell types relevant to the disease. Generally speaking, building disease models with IPSC frequently entails a number of phases, each of which is tailored to a particular disease and cell type.

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