The Mac @TheMac
12 July, 07:43

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Maybe Herb @maybeherb
12 July, 08:10
In response The Mac to his Publication
I suspected at the time, why the highest level of assistance for a commoners missing child?

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The Mac @TheMac
12 July, 02:12
In response Maybe Herb to her Publication
The Commission adopted a 5G action plan for Europe in 2016 to ensure the early deployment of 5G infrastructure across Europe. The objective of the action plan was to start launching 5G services in all EU Member States by end 2020 at the latest.7 Jun 2022
https://digital-strategy.e... › ...
5G | Shaping Europe's digital future - European Union

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Maybe Herb @maybeherb
12 July, 03:08
In response The Mac to his Publication
and the connection is?

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The Mac @TheMac
13 July, 05:50
In response Maybe Herb to her Publication
Ion-ion interactions are an attractive force between ions with opposite charges. They are also referred to as ionic bonds and are the forces that hold together ionic compounds.

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The Mac @TheMac
13 July, 05:51
In response The Mac to his Publication

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The Mac @TheMac
13 July, 05:55
In response The Mac to his Publication

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The Mac @TheMac
13 July, 05:58
In response The Mac to his Publication
Recently, optical stimulation1,2,3 has begun to unravel the neuronal processing that controls certain animal behaviours4,5. However, optical approaches are limited by the inability of visible light to penetrate deep into tissues. Here, we show an approach based on radio-frequency magnetic-field heating of nanoparticles to remotely activate temperature-sensitive cation channels in cells. Superparamagnetic ferrite nanoparticles were targeted to specific proteins on the plasma membrane of cells expressing TRPV1, and heated by a radio-frequency magnetic field. Using fluorophores as molecular thermometers, we show that the induced temperature increase is highly localized. Thermal activation of the channels triggers action potentials in cultured neurons without observable toxic effects.

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The Mac @TheMac
13 July, 06:01
In response The Mac to his Publication
The use of semiconductor quantum dots (qdots) as optical imaging agents is well established; however, the use of these nanoparticles to form interfaces that interact directly with cells has proved more challenging. Our goal has been to create specific nanoparticle-neuronal receptor interfaces that can be optically excited to elicit an action potential. Our preliminary calculations showed the possible feasibility of this approach, even in the presence of Debye screening. We therefore have developed several methods of nanoparticle-directed binding to cell surfaces. These methods can produce either nonspecific or directed interfaces, only nanometers from the receptor of interest. These techniques are versatile and have allowed us to achieve a variety of nanoparticle-neuron interfaces; however, they are also subject to inherent limitations at the cell surface, including endocytosis.

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The Mac @TheMac
To address this concern, we have developed tethered nanoparticle films, which may be able to interact nonspecifically with receptors of nerve cells cultured on their surfaces. These films were found to be extremely stable in cell culture media, but degraded within 3-5 days in primary neuron cultures. Here, we discuss the initial development of tethered quantum dot films produced in our laboratory and their compatibility with cell culture conditions.
06:02 AM - Jul 13, 2022
In response The Mac to his Publication
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The Mac @TheMac
13 July, 06:04
In response The Mac to his Publication

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The Mac @TheMac
13 July, 06:05
In response The Mac to his Publication

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